Algorithms for Inferring Evolution and Migration of Tumors

Speaker: Ben Raphael

Date: Wednesday, April 05, 2017

Time: 11:30 AM to 1:00 PM Note: all times are in the Eastern Time Zone

Refreshments: 11:15 AM

Public: Yes

Location: 32-G575

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Host: Bonnie Berger

Contact: Patrice Macaluso, 617-253-3037, macaluso@csail.mit.edu

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Reminders to: bioinfo-seminar@lists.csail.mit.edu, seminars@csail.mit.edu, bergerlab-core@mit.edu

Reminder Subject: TALK: Algorithms for Inferring Evolution and Migration of Tumors

Cancer is an evolutionary process driven by somatic mutations that accumulate in a population of cells that form a primary tumor. In later stages of cancer progression, cells migrate from a primary tumor and seed metastases at distant anatomical sites. I will describe algorithms to reconstruct this evolutionary process from DNA sequencing data of tumors. These algorithms address challenges that distinguish the tumor phylogeny problem from classical phylogenetic tree reconstruction, including challenges due to mixed samples and complex migration patterns.

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See other events that are part of the Bioinformatics Seminar Series 2017.

Created by Patrice Macaluso at Wednesday, March 22, 2017 at 2:29 PM.